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Biotechnology / Induced pluripotent stem cell / Cell biology / Muscular system / Long QT syndrome / HERG / Cellular differentiation / E-4031 / Cardiac muscle / Biology / Developmental biology / Stem cells


RESEARCH ARTICLE Disease Models & Mechanisms 5, [removed]doi:[removed]dmm[removed]Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in
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Document Date: 2014-06-10 08:29:28


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Finnzymes Oy / Hospira / Orion Corporation / Roche Diagnostics / Millipore / Sigma-Aldrich / Biologists Ltd / Orion Pharma / Cambrex / LQT2 / SPSS / IBM / IgG / LQT2 iPSC-CMs / Medix Laboratories / Fermentas GmbH / Alomone Labs / Creative Commons / Fluor / iPSC-CMs / /

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Kyoto University / Tampere University of Technology / WiCell Research Institute / Gladstone Institute of Cardiovascular Disease / University of California / Tampere University Hospital / Hubrecht Institute / University of Helsinki / Institute of Biomedical Technology / University of Tampere / /

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pharmaceutical industry / mutation carrier / chemical entities / iPSC technology / myosin heavy chain / pharmaceutical / /

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ventricular tachycardia / Teratomas / torsades de pointes / seizures / ventricular223 RESEARCH ARTICLE Human disease / teratoma formation / appropriate disease / cardiac arrhythmia / disorder / RESEARCH ARTICLE Human disease / Teratomas / Tumor / genetic disease / sudden cardiac death / hypokalemia / few neurological diseases / Timothy syndrome / Mechanisms DMM SUMMARY Long QT syndrome / syncope / torsade de pointes / retrovirus infection / lentivirus infection / dissociation / long QT syndrome / Teratoma / disease / noncardiac disorders / Mechanisms DMM Human disease / LEOPARD syndrome / syndrome / /

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antibiotics / /

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J.K. / /

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University of California / Center for iPS Cell Research and Application / University of Tampere / Gladstone Institute of Cardiovascular Disease / Department of Medicine / Tampere University of Technology / Finnish Foundation / Kyoto University / University of Helsinki / Blood Service / Tampere University Hospital / Finnish Red Cross / Department of Biomedical Engineering / Harvard / Heart Center / Institute of Biomedical Technology / and 2BioMediTech / /

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Chris Schlieve / Gene Endodermal / Takayuki Tanaka / Timo Otonkoski / Tester / Christine Mummery / Kenta Nakamura / Mayo Clin / /

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D. J. / RT / Author / Major / forward / leader / /

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California / /

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genotyping / stem cells / gene expression / genotype / gel electrophoresis / antibodies / Biotechnology / iPSC technology / drug development / /

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