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Neurology / Immune system / Enzymes / Galactosides / Blood–brain barrier / Amyloid / Beta amyloid / Beta-galactosidase / Immunohistochemistry / Biology / Anatomy / Glycoproteins


A Carrier for Non-Covalent Delivery of Functional BetaGalactosidase and Antibodies against Amyloid Plaques and IgM to the Brain Gobinda Sarkar1,2*, Geoffry L. Curran3, Eric Mahlum1, Teresa Decklever4, Thomas M. Wengenack
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Document Date: 2012-06-14 13:10:51


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Rochester / Burlingame / Emeryville / Neuroreport / Samara / /

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IgG / ABC / Vector Laboratories / Proc Natl Acad Sci U S A / Friden / Cell Molecular Analysis Laboratory / Creative Commons / GC EM TD TW AB / GE Healthcare / Jackson Laboratories / De Boer AG / Zlokovic BV / McCormick / Covance / Plenum Publishing Corporation / /

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chemical synthesis / clinical applications / carrier peptide / molecular imaging / pharmaceutical technology / peptide carrier / imaging / chemical linking / ligand-receptor systems / carrier molecule / chemical linkage / affinity transport systems / carrier entity / receptor-ligand systems / radiologic imaging / Final imaging / translational applications / /

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neurodegenerative disease / numerous brain-associated disorders / MS / Alzheimer’s disease / cancer / disease / infection / neurological diseases / disorders / /

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immunotherapy / catheter / Drug targeting / /

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Harvard Medical School / Department of Experimental Pathology / Institutional Animal Care and Use Committee / Massachusetts General Hospital / Department of Orthopedics / Mayo Foundation / Department of Radiology / /

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S. Brimijoin / /

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original author / Editor / Author / /

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K16ApoE injection / sodium pentobarbital / A329101 / Alzheimer / /

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Minnesota / New York / /

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PLoS ONE / /

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Neuroscience / tomography / Antibodies / drug delivery / gene expression / flash / /

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