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Health / Protease inhibitors / Hepatology / Viral hepatitis / Cytokines / Hepatitis / Boceprevir / Telaprevir / Peginterferon alfa-2a / Medicine / Antivirals / Biology


Horizon Scanning Centre March 2015 Simeprevir in combination with sofosbuvir (with or without ribavirin) for chronic hepatitis C
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City

Geneva / Cambridge / London / Edinburgh / /

Company

Jansen Scientific Affairs LLC / NIHR Horizon Scanning Centre TARGET GROUP / Janssen-Cilag International NV / ADVANTAGES If / Gilead Sciences / Hepatitis C Trust / /

Country

United States / Canada / United Kingdom / Spain / Ireland / Wales / /

Currency

GBP / /

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Event

Product Issues / FDA Phase / /

Facility

National Institute / Royal College of General Practitioners / University of Birmingham Email / University of Birmingham / /

IndustryTerm

treatment of hepatitis C / health technology / drug technologies / patient / nihrhsc@contacts.bham.ac.uk Web / NICE technology appraisal / healthcare / medicinal products / literature search / treatment for HCV / technology appraisal / /

MedicalCondition

hepatitis C. Geneva / HIV / influenza-like illness / headache / hepatitis C. National / Nolte E. Hepatitis C. A / nausea / cirrhosis / acute infections / hepatitis C / Hepatitis B / chronic genotype / fatigue / liver cirrhosis / hepatitis C. Expected / End-stage liver disease / chronic HCV infection / constipation / pruritus / liver disease / chronic hepatitis C. January / HCV genotype / insomnia / hepatitis viruses / Janssen Infectious Diseases BVBA / arthralgia / hepatocellular carcinoma / chills / cirrhosis/without cirrhosis / Chronic HCV / neutropenia / HCV / HCV RNA 12 / hepatitis C infection. https / pain / HCV infection / infection / dizziness / cough / depression / rash / chronic hepatitis C / HCV RNA / /

MedicalTreatment

liver transplant / liver transplants / /

Organization

Health & Social Care Information Centre / Royal College of General Practitioners / www.hscic.gov.uk Office / University of Birmingham Email / Office for National Statistics / Horizon Scanning Centre / European Association for the Study of the Liver / NIHR Horizon Scanning Centre / Health Protection Agency / University of Birmingham / National Institute for Health / C. Standards Unit / National Institute for Health Research / National Institute for Health and Clinical Excellence / High Security Infectious Disease Unit / Royal Pharmaceutical Society / European Union / Department of Health / NHS / British HIV association / /

Person

Norris S. Hepatitis / Telaprevir (Incivo) Boceprevir / Ribavirin (Rebetol) Telaprevir / /

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Position

consultant / author / Governor / gov. uk Public Health England / Major / /

Product

peginterferon / ribavirin / Pegasys / Rebetol / blood / TMC435HPC3017 / TMC435HPC3018 / NCT02250807 / TMC435HPC2014 / TMC435HPC2009 / /

Technology

health technology / drug technologies / genotype / /

URL

www.gov.uk/government/news/hepatitis-c-diagnoses-rise-by-a-third-in-england / www.medicines.org.uk/emc/medicine/28539#UNDESIRABLE_EFFECTS / www.medicines.org.uk/emc/medicine/28888#UNDESIRABLE_EFFECTS / www.clinicaltrials.gov/ct2/show/NCT02250807?term=NCT02256176&rank=1 / www.hscic.gov.uk / www.ons.gov.uk / www.medicinescomplete.com/mc/bnf/current / http /

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